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Sequestration

What is sequestration?

Sequestration refers to the process of isolating or containing a specific part of the body or tissue, often to prevent the spread of infection, manage injury, or facilitate healing. It can occur in various parts of the body, such as the spleen or bones, and may involve the trapping or separation of blood cells or tissues.

What causes sequestration?

Sequestration can be caused by a range of factors, including:

  • Traumatic injury: Severe trauma can lead to the isolation or containment of damaged tissue to prevent further harm.

  • Infection: In response to infection, the body may sequester affected tissues to limit the spread of pathogens.

  • Medical procedures: Sequestration may occur as a result of surgical interventions or medical treatments to isolate specific areas for therapeutic purposes.

What are the symptoms of sequestration?

Symptoms of sequestration vary depending on the location and underlying cause but may include:

  • Pain or discomfort in the affected area

  • Swelling or inflammation

  • Restricted movement or function

  • Changes in skin color or temperature

  • Systemic symptoms such as fever or malaise if infection is involved

How to treat sequestration?

Treatment for sequestration depends on the underlying cause and severity of the condition.

Options may include:

  • Conservative management: Rest, immobilisation, and supportive care to promote healing and reduce symptoms.

  • Surgical intervention: In cases of severe injury or infection, surgical procedures may be necessary to remove sequestered tissue or address underlying issues.

  • Medications: Antibiotics or anti-inflammatory drugs may be prescribed to manage infection or inflammation associated with sequestration.

  • Interventional procedures: In some cases, minimally invasive techniques such as drainage or aspiration may be used to address sequestered fluid or tissue.


It's important to consult with a paediatric surgeon for an accurate diagnosis and appropriate treatment of sequestration based on individual circumstances.

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